Survival analysis TSD

A review of methods for undertaking survival analysis for use in an economic evaluation when patient-level data are available and evidence synthesis is not necessary, with recommendations on systematic processes.

TSD 14: Survival analysis for economic evaluations alongside clinical trials – extrapolation with patient-level data (last updated March 2013) (PDF, 395KB)

TSD 14 one page summary (PDF, 102KB)

Related publications

N Latimer (2013) Survival analysis for economic evaluations alongside clinical trials – extrapolation with patient-level data. Inconsistencies, limitations, and a practical guide. Medical Decision Making, 33 (6), pp. 743-754.doi:https://doi.org/10.1177/0272989x12472398

A Bagust, S Beale (2013) Survival analysis and extrapolation modeling of time-to-event clinical trail data for economic evaluation: an alternative approach. Medical Decision Making, 34(3), pp.343351.doi: https://doi.org/10.1177/0272989X13497998

N Latimer (2013) Response to “Survival analysis and extrapolation modeling of time-to-event clinical trial data for economic evaluation: an alternative approach” by Bagust and Beal. Medical Decision Making, 34(3), pp. 279–282.doi:https://doi.org/10.1177/0272989X13511302